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Injection of mite allergen tended to increase the total serum IgE (Fig. 6A) and Dp-specific IgG1 (Fig. 6B). The application of BZK markedly induced total IgE production compared with the Dp + vehicle (p < 0.001). As well, the application of PVP-I but not Et-OH or CHG tended to increase the total IgE level. The Dp-specific IgG1 level substantially increased with the application of BZK, PVP-I, and Et-OH as compared with Dp alone, but the overall relative difference was small. The application of CHG did not induce Dp-specific IgG1 production.. Our results are consistent with our initial hypothesis that psychological factors play a role in the delay, but this study adds to previous knowledge some interesting new evidence of the relationship between decision-making time and both somatic awareness and perceived threat sustaining the “common-sense representation of illness” model 43, 44 and others similar results recently found.45.
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